Tablet press, which is a very important production equipment in the solid dosage process, is widely used in the pharmaceutical industry. RichPacking is a leading pharmaceutical and packaging machinery manufacturer in China. With our more than 30 years of rich experience, we will give a comprehensive and in-depth introduction to tablet presses in this article, hoping to help you with your comprehensive understanding.
A tablet press machine is a mechanical device that can press powders, granules, pellets or mixtures of these into shapes of the same size. The shapes that can be pressed include round, diamond, ring or other irregular shapes; double-layer two-color tablets, three-layer three-color tablets and other multi-layer tablets can also be made, and each layer can be evenly distributed. The final shape of the tablet is achieved by customizing different molds. Many users also need to present their company's LOGO or imprint on the tablet, which can also be achieved through customized molds.
The earliest history of tablet presses began in the early 19th century, but the earliest tablets were made purely by hand, that is, they were squeezed by hand using simple tools. This method is very laborious, the output is very low, and the shape and weight of the tablets cannot be maintained at a stable level.
In 1854, an American named Ezra Perry invented a manual tablet press and applied for a patent. The general working process is to add powder manually, press manually, and then manually produce tablets. Although the whole process needs to be done manually, it has already opened the precedent of mechanical structure tablet presses.
In the 20th century, after the two world wars, with the advancement of science and technology and the development of the pharmaceutical industry, pharmaceutical tablet presses also developed. The rotary tablet press was first invented in Europe, and the production efficiency was greatly improved. The additional functions are becoming more and more abundant, such as forced automatic feeding system and overload protection system.
Although the most basic working principle of the tablet press has not changed since its invention, after entering the 21st century, the auxiliary functions have become more and more intelligent. Automatic waste rejection system, pressure control system, hardness detection system, and more powerful PLC system all enable the machine to achieve continuous, stable and high-speed production.
After understanding the development history of tablet press, let's take a deeper look at the working principle of tablet press.
The working principle of tablet press can be summarized in three steps very simply. The following are the specific steps of the working principle of tablet press: feeding, pressing, and tableting.
(1)Feeding: Add powder or granular materials to the middle die forming position of the tablet press.
(2)Pressing: The upper punch and the lower punch press the powder, granules or mixture filled in the mold into tablets through force.
(3)Tablet discharge: After the tablet is pressed, it is ejected from the mold.
From the above, we know that the basic principle of tablet press is actually very simple. Its main types can be divided into manual tablet press, single punch tablet press, basket punch tablet press, and rotary tablet press.
It is a tool that uses manual force to press tablets, and the whole process is completed manually. Manually add powder, manually press, and finally take out the pressed tablets by hand. This is the most basic type.
This is a very small tablet press with only one tablet pressing station, so the production efficiency is very low. However, it occupies a small area, is simple to operate and maintain, and is suitable for small-scale production in ordinary laboratories, pharmacies or backward areas.
The transmission part of this tablet press is similar to a flower basket, so it is named after it. It is usually used to press large tablets, such as fish bait blocks. . Since there is only one tablet pressing station, the output of the flower basket punch tablet press is not high. Its advantages are high pressing pressure, the mold can be set very large, and large-sized tablets can be formed. Since the flower basket punch tablet press cannot meet the GMP production requirements, with the development of science and technology and the strictness of production standards in various countries around the world, this model can no longer be used in the pharmaceutical industry with the largest tablet pressing demand.
The rotary tablet press is currently the most commonly used tablet press, mainly used for mass production in the pharmaceutical, food, health care products, and chemical industries. The main structure includes a turntable, multiple sets of molds, a transmission structure and a control system.
During its working process, multiple sets of molds rotate on the turntable. Through the horizontal movement of the upper and lower punches on the guide rails, when they rotate to a certain position, the upper and lower punches will press the material into tablets in the middle mold. This rotating operation mode makes its production efficiency much higher than other models. By increasing the number of molds and increasing the speed of the turntable, more efficient production efficiency can be achieved.
In addition to high output, through PLC intelligent system programming, the rotary tablet press can also be configured with additional functions according to actual needs, achieving the advantages of high intelligence and convenience and practicality. Without the need to make complex adjustments to the machine architecture, by reasonably setting parameters on the HMI interface, it is very simple to adjust the thickness, hardness and other parameters of the tablets.
The current rotary tablet press is equipped with a variety of data interfaces, which transmit data through network cables, TYPE-C interfaces, and USB interfaces to upload and download data, providing a strong basic support for pharmaceutical companies to achieve industrial 4.0 upgrades.
The most widely used tablet presses are still in the pharmaceutical industry, so production efficiency and precision are the main development trends, and rotary tablet presses are the correct development direction of the industry.
(1)Intelligence: The development of AI today drives industrial equipment towards mature automation. The design of tablet presses will require more advanced programming design, with the goal of improving drug quality and production efficiency.
(2)Production efficiency: In the future, the concept of health will continue to become more and more popular, and the demand for health products and tablets will increase, so the production of pharmaceutical equipment must be more and more efficient. Tablet presses that can be used for large-scale and continuous production are important research and development directions.
(3)Precise tablet weight: The development of pharmaceutical formulas brings clearer medical and health product intake, so the weight of a single tablet and the tablet hardness that affects the sustained release of the tablet must be at a very stable level, so a rotary tablet press with tablet weight detection and hardness detection is a key device in the future.
In general, tablet presses are important equipment in the pharmaceutical, food, health care, chemical and other industries. Fully understand the working principle and types of tablet presses in advance, so that when you need to purchase, you will know what points to pay attention to. I hope this article can help you. If you are interested in learning more about tablet presses, please contact us. We are very happy to provide you with more help.
E-mail : manager@richpacking.cn
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